I have a history of DVT, so I like to wear these when working (WFH tech job, 8 hours at a computer).
I found that these ran a bit on the small side compared to the sizing chart, or the break between sizes should be adjusted a bit for those on the border of a size change. I wish I would have gotten the next size up (they were too tight around the upper knee area for me. Measure carefully and if you are on the cusp of a size, I would guess that the next size up would be best.
I found that any nail would cause a run, or any sort of poke in the fabric more so than another set that I have, but these are much softer material than the others that I own. I like the anti slip at the top of the stocking, I found that it really does help keep it from falling down during the day.